PICSI - Physiological ICSI
PICSI improves fertilization outcomes by selecting the most mature and healthy sperm using a natural hyaluronic acid binding method.
What is PICSI?
PICSI (Physiological ICSI) is an advanced version of ICSI where sperm are selected based on their ability to bind with hyaluronic acid (HA) — a component naturally found in the egg membrane. This method helps identify mature, DNA-intact sperm, which are more likely to produce healthy embryos.
DNA-Intact Sperm
Sperm that bind to HA have lower DNA fragmentation and better fertilization potential.
Improved Embryo Quality
Better sperm selection results in higher-quality embryos and lower miscarriage risk.
Safer Selection
Mimics natural selection process within the female body without using artificial techniques.
Who Should Consider PICSI?
- History of failed fertilization or poor embryo quality in ICSI
- Unexplained infertility or recurrent IVF failure
- High DNA fragmentation in semen analysis
- Advanced paternal age
PICSI Procedure Overview
- Egg retrieval is performed as in ICSI.
- Sperm are exposed to a hyaluronic acid plate.
- Sperm that bind naturally to HA are selected under microscope.
- Selected sperm are injected into eggs via ICSI.
- Fertilized embryos are monitored and transferred.
Why Choose DAARA for PICSI?
- State-of-the-art HA binding chambers
- High success rate with recurrent ICSI failures
- Custom sperm analysis and counseling
- Advanced lab with stringent embryo monitoring
Frequently Asked Questions
Does PICSI guarantee pregnancy?
No, but it significantly improves fertilization and embryo quality in suitable cases.
Is PICSI more expensive than ICSI?
It adds a small cost but can save time and effort in repeated IVF cycles.
Can PICSI be used with donor sperm?
Yes. In fact, it ensures only healthy donor sperm are selected during ICSI.